Development Programs

Bile Acid Receptor Activators

Lead candidate JO-001, a modified bile acid, is designed to activate bile acid receptor signaling. This preclinical drug candidate is being developed to treat or prevent fatty liver disease, obesity, and type 2 diabetes.

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Liver–Brain Neuroimmune Axis Modulators

Therapeutics targeting hepatic neuroimmune signaling and the vagal liver–brain circuit for neurodegenerative disease.

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Digital Research Tools

Mobile applications that put everyday molecular biology workflows in a researcher’s pocket, including Gene Search for NCBI gene and protein lookup and Plasmid Editor for cloning design.

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